Biocuration, Translation, Integration

Our team of expert biological curators, augmented by computational tools, maintain and enhance a knowledge extraction and refinement process that delivers an ever-growing set of relevant biological data and its provenance.

Ontologies, Modeling, Knowledge Representation

We develop and promote the use of shared ontologies to describe knowledge in an open and extensible model that is targeted towards machine reasoning. We develop, adapt and apply innovative scientific knowledge management theory and technology to provide computational semantic bridges between disparate knowledge sources.

Bioinformatics, Analysis, Integration

We seek to enable bioinformatic reasoning and clinical decision-making using all the species as well as associated bioinformatic data, including genes, phenotypes, chemistry, drugs, and much more.

About Us

We have forged a cross-disciplinary team of biologists, ontologists, biocurators, computer scientists, and clinicians whose goal is to develop open-source informatics solutions that can transform disease diagnosis and discovery. TISL is not a commercial entity; it is not even a legal entity unto itself, but rather a brand new cross-departmental team within Oregon State University.

Melissa Haendel

Director of Translational Data Science at OSU's Center for Genome Research and Biocomputing

Principal Investigator at the Linus Pauling Institute

Associate Professor in the Department of Environmental Toxicology and the School of Biological and Population Health Sciences

Director of OHSU's Translational and Integrative Sciences Lab

Co-director of the NCATS-funded Biomedical Data Translator at OHSU's Oregon Clinical & Translational Research Institute (OCTRI)

Matthew Brush



Robin Champieux

Scholarly Communication Librarian


Lauren Chan

Graduate Student


Tom Conlin



Shahim Essaid

Semantic Engineer


Julie McMurry

Associate Director, TISL


Moni Munoz-Torres

Program Manager


Kent Shefchek

Bioinformatics Engineer


Anne Thessen

Biodiversity Informaticist


Nicole Vasilevsky

Lead Biocurator


Marijane White

Linked Data Librarian


Our Global Presence

Our core team is based in the beautiful Pacific Northwest at two powerful institutions: Oregon State University and Oregon Health and Sciences University.

Linus Pauling Science Center

CGRB at OSU in the Linus Pauling Institute

Our research facilities are located in the Center for Genome Research and Biocomputing (CGRB) on the Oregon State University campus in the Linus Pauling Institute

School of Nursing

OCTRI at OSHU in the School of Nursing

Our Oregon Health & Science University research facilities are located at OCTRI in the School of Nursing.